关键词: exposures interstitial lung disease pancreatic cancer vitamins and supplements

Mesh : Adenocarcinoma Complementary Therapies / adverse effects Fatal Outcome Humans Lung / diagnostic imaging pathology Lung Neoplasms / pathology secondary Male Middle Aged Pancreatic Neoplasms / pathology therapy Patient Compliance Tomography, X-Ray Computed Vaping / adverse effects Pancreatic Neoplasms

来  源:   DOI:10.1136/bcr-2019-231356   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
The use of complementary and alternative medicine (CAM) among cancer patients is widespread. Using these therapies may lead to treatment delays or confound the clinical picture when problems arise. Inquiry regarding CAM therapies used is an important part of a thorough history for any cancer patient. A 48-year-old man with a history of stage IV pancreatic adenocarcinoma was referred for a second opinion for a worsening dry cough in the setting of cavitary ground-glass opacities and non-cavitating nodules found on chest CT. Previous workup was non-diagnostic and his CT findings were atypical for pulmonary metastasis. Due to his extensive alternative therapy use, he was diagnosed with interstitial lung disease (ILD). Flexible bronchoscopy with transbronchial cryobiopsies revealed adenocarcinoma with intestinal/pancreatobiliary differentiation, consistent with metastatic pancreatic cancer. Adjacent alveolar parenchyma was without evidence of ILD. Atypical CT patterns of pulmonary metastasis should lead to an investigation regarding other possible causes.
摘要:
在癌症患者中广泛使用补充和替代医学(CAM)。当出现问题时,使用这些疗法可能会导致治疗延迟或混淆临床表现。关于使用的CAM疗法的询问是任何癌症患者全面病史的重要部分。一名有IV期胰腺腺癌病史的48岁男子因在胸部CT上发现空洞性毛玻璃混浊和非空洞性结节的情况下干咳恶化而被推荐接受第二意见。先前的检查不可诊断性,他的CT发现不典型的肺转移。由于他广泛使用替代疗法,他被诊断为间质性肺病(ILD)。经支气管冷冻活检的柔性支气管镜检查显示腺癌伴肠/胰胆管分化,与转移性胰腺癌一致。相邻的肺泡实质没有ILD的证据。肺转移的非典型CT模式应导致对其他可能原因的调查。
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