关键词: Candida Source Control intraabdominal candidiasis septic shock

Mesh : Antifungal Agents / administration & dosage therapeutic use Biomarkers Candidiasis, Invasive / drug therapy mortality physiopathology prevention & control Critical Illness Humans Intensive Care Units Intraabdominal Infections / drug therapy mortality physiopathology prevention & control Mannans / immunology Procalcitonin / metabolism Risk Factors Severity of Illness Index beta-Glucans / metabolism

来  源:   DOI:10.1080/21548331.2019.1677032   PDF(Sci-hub)

Abstract:
A high prevalence of invasive candidiasis has been reported in recent years. Patients admitted to an intensive care unit are at the highest risk for invasive candidiasis, mostly due to the severity of their disease, immune-suppressive states, prolonged length of stay, broad-spectrum antibiotics, septic shock, and Candida colonization. Intraabdominal candidiasis comprises a range of clinical manifestations, from just the suspicion based on clinical scenario to fever, leukocytosis, increase in biomarkers to the isolation of the responsible microorganism. In critically ill patients with IAC prompt treatment and adequate source control remains the ultimate goal.
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