PDF(Pubmed)
Abstract：
Urinary tract infections (UTIs) are among the most common microbial infections in humans and represent a substantial burden on the health care system. UTIs can be uncomplicated, as when affecting healthy individuals, or complicated, when affecting individuals with compromised urodynamics and/or host defenses, such as those with a urinary catheter. There are clear differences between uncomplicated UTI and catheter-associated UTI (CAUTI) in clinical manifestations, causative organisms, and pathophysiology. Therefore, uncomplicated UTI and CAUTI cannot be approached similarly, or the risk of complications and treatment failure may increase. It is imperative to understand the key aspects of each condition to develop successful treatment options and improve patient outcomes. Here, we will review the epidemiology, pathogen prevalence, differential mechanisms used by uropathogens, and treatment and prevention of uncomplicated UTI and CAUTI.
摘要：
尿路感染（UTI）是人类最常见的微生物感染之一，对医疗保健系统构成了沉重负担。UTI可以不复杂，就像影响健康个体一样，或者复杂，当影响泌尿动力学和/或宿主防御受损的个体时，比如那些有导尿管的。无并发症UTI与导管相关UTI(CAUTI)的临床表现有明显差异,致病生物，和病理生理学。因此,不复杂的UTI和CAUTI不能类似地处理，或并发症和治疗失败的风险可能增加。必须了解每种情况的关键方面，以开发成功的治疗方案并改善患者的预后。这里,我们将回顾流行病学，病原体流行，尿路病原体使用的差异机制，以及治疗和预防简单的UTI和CAUTI。
