Abstract：
BACKGROUND: Although expression of WWOX was extensively studied in different tumors, WWOX gene expression in acute myeloid leukemia is not well-known or recognized.
METHODS: Fifty control donors and fifty acute myeloid leukemia patients were enrolled in this research. The levels of WWOX gene in all participants were detected by RT-qPCR.
RESULTS: Levels of WWOX gene in the AML group were significantly lower as compared to the control group (0.27205 ± 1.19812 vs. 10.501 ± 9.0338, respectively, p < 0.001**).
CONCLUSIONS: Decreased expression of WWOX gene ran parallel with acute myeloid leukemia regression.
METHODS: Fifty control donors and fifty acute myeloid leukemia patients were enrolled in this research. The levels of WWOX gene in all participants were detected by RT-qPCR.
RESULTS: Levels of WWOX gene in the AML group were significantly lower as compared to the control group (0.27205 ± 1.19812 vs. 10.501 ± 9.0338, respectively, p < 0.001**).
CONCLUSIONS: Decreased expression of WWOX gene ran parallel with acute myeloid leukemia regression.
摘要：
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