关键词: asymptomatic bacteriuria bacteriuria cystitis diabetes endourologic surgery long-term care neurogenic bladder nursing home older adults pregnancy pyelonephritis renal transplant spinal cord injury urinary catheter urinary tract infection urologic devices

Mesh : Adult Aged Anti-Bacterial Agents / therapeutic use Antimicrobial Stewardship Asymptomatic Infections Bacteriuria / diagnosis drug therapy Child Disease Management Female Humans Male Neutropenia / complications Pregnancy Prevalence Transplant Recipients Urinary Tract Infections / drug therapy microbiology

来  源:   DOI:10.1093/cid/ciz021   PDF(Sci-hub)

Abstract:
Asymptomatic bacteriuria (ASB) is a common finding in many populations, including healthy women and persons with underlying urologic abnormalities. The 2005 guideline from the Infectious Diseases Society of America recommended that ASB should be screened for and treated only in pregnant women or in an individual prior to undergoing invasive urologic procedures. Treatment was not recommended for healthy women; older women or men; or persons with diabetes, indwelling catheters, or spinal cord injury. The guideline did not address children and some adult populations, including patients with neutropenia, solid organ transplants, and nonurologic surgery. In the years since the publication of the guideline, further information relevant to ASB has become available. In addition, antimicrobial treatment of ASB has been recognized as an important contributor to inappropriate antimicrobial use, which promotes emergence of antimicrobial resistance. The current guideline updates the recommendations of the 2005 guideline, includes new recommendations for populations not previously addressed, and, where relevant, addresses the interpretation of nonlocalizing clinical symptoms in populations with a high prevalence of ASB.
摘要:
无症状性菌尿(ASB)是许多人群中的常见发现,包括健康女性和有潜在泌尿系统异常的人。美国传染病学会2005年指南建议,在接受侵入性泌尿外科手术之前,应仅在孕妇或个人中筛查和治疗ASB。不建议健康女性、老年女性或男性或糖尿病患者接受治疗。留置导管,或者脊髓损伤。该指南没有针对儿童和一些成年人群,包括中性粒细胞减少症患者,实体器官移植,和非泌尿外科手术.在指南发布后的几年里,与ASB相关的更多信息已经可用。此外,ASB的抗菌治疗已被认为是不适当使用抗菌药物的重要原因,这促进了抗菌素耐药性的出现。现行准则更新了2005年准则的建议,包括针对以前未解决的人群的新建议,and,如果相关,解决了ASB高患病率人群中临床症状非本地化的解释。
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