关键词: diagnosis radiotherapy surgery treatment vestibular schwannoma

Mesh : Humans Neuroma, Acoustic / diagnosis therapy

来  源:   DOI:10.1093/neuonc/noz153   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
The level of evidence to provide treatment recommendations for vestibular schwannoma is low compared with other intracranial neoplasms. Therefore, the vestibular schwannoma task force of the European Association of Neuro-Oncology assessed the data available in the literature and composed a set of recommendations for health care professionals. The radiological diagnosis of vestibular schwannoma is made by magnetic resonance imaging. Histological verification of the diagnosis is not always required. Current treatment options include observation, surgical resection, fractionated radiotherapy, and radiosurgery. The choice of treatment depends on clinical presentation, tumor size, and expertise of the treating center. In small tumors, observation has to be weighed against radiosurgery, in large tumors surgical decompression is mandatory, potentially followed by fractionated radiotherapy or radiosurgery. Except for bevacizumab in neurofibromatosis type 2, there is no role for pharmacotherapy.
摘要:
与其他颅内肿瘤相比,为前庭神经鞘瘤提供治疗建议的证据水平较低。因此,欧洲神经肿瘤学协会的前庭神经鞘瘤工作组评估了文献中的数据,并为卫生保健专业人员提出了一系列建议.前庭神经鞘瘤的放射学诊断是通过磁共振成像进行的。并不总是需要诊断的组织学验证。目前的治疗选择包括观察,手术切除,分割放疗,和放射外科。治疗的选择取决于临床表现,肿瘤大小,和治疗中心的专业知识。在小肿瘤中,必须权衡观察和放射外科,在大肿瘤手术减压是强制性的,可能是分割放疗或放射外科。除了贝伐单抗治疗2型神经纤维瘤病外,药物治疗没有作用。
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