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Abstract：
BACKGROUND: A primordial odontogenic tumor (POT) is a rare, benign, mixed epithelial and mesenchymal odontogenic tumor that has been included as a new entity in the latest World Health Organization (WHO) classification (2017). POT consists of dental papilla-like myxoid connective tissue covered with a delicate membrane of ameloblastic epithelium. Only 15 cases have been documented worldwide, and here, we report the sixteenth case and the first one of South Korea.
METHODS: An asymptomatic lesion was discovered as an incidental radiographic finding in a 10-year-old boy. The patient had no complaints about the lesion. Cone-beam computerized tomograms revealed a round cavity with a defined cortical border measuring approximately 5 × 5 × 5 mm in size. The lesion was a POT. The patient was treated with enucleation. The tumor showed no recurrence for one year.
CONCLUSIONS: This is the first report of POT in South Korea using the novel diagnosis of POT after it was recognized and defined in the latest WHO classification. This novel diagnosis will be useful for pathologists and clinicians in diagnosing and differentiating this new and rare disease from other odontogenic tumors.
METHODS: An asymptomatic lesion was discovered as an incidental radiographic finding in a 10-year-old boy. The patient had no complaints about the lesion. Cone-beam computerized tomograms revealed a round cavity with a defined cortical border measuring approximately 5 × 5 × 5 mm in size. The lesion was a POT. The patient was treated with enucleation. The tumor showed no recurrence for one year.
CONCLUSIONS: This is the first report of POT in South Korea using the novel diagnosis of POT after it was recognized and defined in the latest WHO classification. This novel diagnosis will be useful for pathologists and clinicians in diagnosing and differentiating this new and rare disease from other odontogenic tumors.
摘要：
背景：原始牙源性肿瘤（POT）是一种罕见的，良性,混合上皮和间充质牙源性肿瘤已被列为最新的世界卫生组织（WHO）分类（2017）的新实体。POT由牙乳头状粘液样结缔组织组成，上面覆盖着精致的成釉细胞上皮膜。全世界只记录了15例，在这里,我们报告了第16例和第一例韩国。
方法：在一个10岁的男孩中发现了一个无症状的影像学表现。患者没有关于病变的抱怨。锥形束计算机断层图像显示一个圆形空腔，其定义的皮质边界尺寸约为5×5×5mm。病变是POT。患者接受了摘除治疗。肿瘤一年无复发。
结论：这是韩国在最新的WHO分类中得到认可和定义后，首次使用POT的新诊断进行POT的报告。这种新的诊断将有助于病理学家和临床医生诊断和区分这种新的和罕见的疾病与其他牙源性肿瘤。
方法：在一个10岁的男孩中发现了一个无症状的影像学表现。患者没有关于病变的抱怨。锥形束计算机断层图像显示一个圆形空腔，其定义的皮质边界尺寸约为5×5×5mm。病变是POT。患者接受了摘除治疗。肿瘤一年无复发。
结论：这是韩国在最新的WHO分类中得到认可和定义后，首次使用POT的新诊断进行POT的报告。这种新的诊断将有助于病理学家和临床医生诊断和区分这种新的和罕见的疾病与其他牙源性肿瘤。
