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Abstract：
Introduction: Different yellow lasers have been successfully used for the treatment of vascular lesions. This study is aimed to ascertain the role and efficiency of copper vapor lasers (CVLs) and pulsed dye lasers (PDLs) for the treatment of vascular lesions using numerical modeling and to compare results with our clinical experience. In this study we aimed to develop criteria for the choice of more efficient laser exposure mode, investigate more relevant modes of laser irradiation to ensure selective photothermolysis of target vessels, and compare the CVL and PDL efficiency in the course of patients with skin vascular lesions (SVL) treatment. Methods: We performed numerical simulation of the processes of heating a vessel with CVL and PDL to temperatures at which its coagulation could occur. Calculated fluencies were compared with clinical results of laser therapy performed on 1242 patients with skin hemangiomas and vascular malformations (SHVM), including 635 patients treated with CVL and 607 patients treated with PDL. PDL and CVL provided excellent results in 40 and ten days after treatment. The treatment was not painful. Patients did not need anesthesia. Postoperative crusts were greater with PDL than with CVL. Results: Results of computer simulation of a selective vessel heating using PDL and CVL radiation are presented. By results obtained, depth of the location and sizes of vessels that could be selectively heated to more than 75°C are determined. Conclusion: Based on calculated and clinical data, the heating mode for dysplastic vessels using a series of CVL micropulses could be regarded to be safer and more efficient than the mode of a PDL short, powerful pulse.
摘要：
简介：不同的黄色激光已成功用于血管病变的治疗。这项研究旨在确定铜蒸气激光器（CVL）和脉冲染料激光器（PDL）的作用和效率在血管病变的治疗中使用数值模型，并将结果与我们的临床经验进行比较。在这项研究中，我们旨在制定选择更有效的激光曝光模式的标准，研究更多相关的激光辐照模式，以确保目标血管的选择性光热解，并比较CVL和PDL在皮肤血管病变(SVL)患者治疗过程中的有效率。方法：我们对使用CVL和PDL加热容器至可能发生凝结的温度的过程进行了数值模拟。将计算的流畅性与对1242例皮肤血管瘤和血管畸形（SHVM）患者进行激光治疗的临床结果进行比较，包括635例接受CVL治疗的患者和607例接受PDL治疗的患者。PDL和CVL在治疗后40天和10天提供了优异的结果。治疗并不痛苦。患者不需要麻醉。PDL术后结皮大于CVL。结果：给出了使用PDL和CVL辐射进行选择性容器加热的计算机模拟结果。根据获得的结果，确定可选择性地加热到超过75°C的容器的位置深度和尺寸。结论：根据计算和临床数据，使用一系列CVL微脉冲的发育不良血管加热模式可以被认为比PDL短模式更安全，更有效，强大的脉冲。
