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Abstract：
Primary sclerosing cholangitis (PSC) is a chronic, idiopathic, cholestatic liver disease characterized by inflammation and fibrosis of the intrahepatic and/or extrahepatic bile ducts. It can affect individuals of all age groups and gender, has no established pharmacotherapy, and is associated with a variety of neoplastic (e.g. cholangiocarcinoma) and non-neoplastic (e.g. dominant strictures) hepatobiliary complications. Given these considerations, endoscopy plays a major role in the care of patients with PSC. In this review, we discuss and provide updates regarding endoscopic considerations in the management of hepatobiliary manifestations and complications of PSC. Where evidence is limited, we suggest pragmatic approaches based on currently available data and expert opinion.
摘要：
原发性硬化性胆管炎(PSC)是一种慢性,特发性,胆汁淤积性肝病的特征是肝内和/或肝外胆管的炎症和纤维化。它可以影响所有年龄组和性别的个人，没有既定的药物治疗，并且与各种肿瘤性（例如胆管癌）和非肿瘤性（例如显性狭窄）肝胆并发症有关。鉴于这些考虑,内窥镜检查在PSC患者的护理中起着重要作用。在这次审查中,我们讨论并提供有关PSC肝胆表现和并发症的内镜治疗注意事项的最新信息.如果证据有限，我们建议基于现有数据和专家意见的务实方法。
