PDF(Pubmed)
Abstract：
An estimated 60% of the world\'s population lives in Asia, where the incidence of neural tube defects is high. Aware that tethered cord syndrome (TCS) is an important comorbidity, the purpose of this systematic review was to explore the treatment of TCS among individuals living with spina bifida (SB) in Asia. MEDLINE and Embase databases were searched for relevant studies published from January 2000 to June 2018. Search terms such as \'spinal dysraphism,\' \'spinabifida,\' \'diastematomyelia,\' \'lipomeningocele,\' \'lypomyelomeningocele,\' \'meningomyelocele,\' and \'tethered cord syndrome\' were used in diverse combinations. Of the 1,290 articles that were identified in accordance with PRISMA (Preferred Items for Systematic Reviews and Meta-Analyses) guidelines, 15 Asia-based studies met the inclusion criteria. Significant differences in the diagnostic criteria and management of TCS were documented. As the surgical techniques for prenatal closure of the spinal defect continue to evolve, their adoption internationally is likely to continue. In this setting, a clear and evidence-based approach to the definition and management of TCS is essential. The recent publication by the Spina Bifida Association of America of their updated care guidelines may serve as a tool used to promote a systematized approach to diagnosing and treating TCS among individuals with SB in the region, as well as globally.
摘要：
估计全世界60%的人口生活在亚洲,神经管缺陷的发生率很高。意识到脊髓栓系综合征（TCS）是一种重要的合并症，本系统综述的目的是探讨亚洲脊柱裂(SB)患者的TCS治疗方法.在MEDLINE和Embase数据库中搜索了2000年1月至2018年6月发表的相关研究。诸如“脊髓发育不良”之类的搜索词，\'\'spinabifida,\'\'脊髓纵裂,\'\'脂膜膨出,脊髓膜膨出,脑膜脊髓膨出,\'和\'系绳综合征\'以不同的组合使用。在根据PRISMA（系统审查和荟萃分析的首选项目）指南确定的1,290篇文章中，15项亚洲研究符合纳入标准。记录了TCS的诊断标准和管理方面的显着差异。随着产前闭合脊柱缺损的手术技术的不断发展，它们在国际上的采用可能会继续。在此设置中，一个明确的和基于证据的方法来定义和管理TCS是至关重要的。美国脊柱裂协会最近发布的最新护理指南可以作为一种工具，用于促进在该地区患有SB的个体中诊断和治疗TCS的系统化方法。以及全球。
