关键词: adult intensive care mechanical ventilation public health vaccination/immunisation

Mesh : Aged Anti-Bacterial Agents / therapeutic use Deglutition Disorders / etiology Female Gastrostomy Humans Metronidazole / therapeutic use Respiratory Insufficiency / etiology Tetanus / complications drug therapy Tetanus Antitoxin / therapeutic use Tetanus Toxoid / therapeutic use Tracheostomy

来  源:   DOI:10.1136/bcr-2019-229502   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
A 78-year-old woman with no known medical history presented with severe neck pain that began 4 days prior to admission located in the paraspinal cervical region radiating to the shoulders, legs and back. She had associated stiffness of her neck and progression of pain to her jaw and throat with progression to generalised body spasms with lower extremity stiffness and weakness that limited her ability to walk. She quickly developed dysphagia and odynophagia with subsequent generalised spasms and profound hypoxic respiratory failure requiring nasotracheal intubation. The presumptive diagnosis of tetanus was made and she was given tetanus toxoid immune globulin and Tdap vaccine. She was managed in the intensive care unit and after a week of admission, required a tracheostomy and gastrostomy tube placement. She required a prolonged hospitalisation stay of 21 days before being transferred to a long-term vent facility.
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