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Abstract：
Conjunctival papilloma is an acquired benign squamous cell tumor that can present at any age, but most frequently in the third and fourth decades of life. Papillomas have been associated with human papilloma virus (HPV) infection, usually types 6 and 11. Although histopathological diagnosis remains the gold standard, the advent of newer non-invasive imaging modalities such as optical coherence tomography (OCT) is transforming the way we diagnose and treat ocular surface tumors, including conjunctival papilloma. Management of these lesions can prove a challenge to the treating physician since not all lesions respond to medical and/or surgical therapy and in fact may worsen after surgical manipulation. In this review, the epidemiology, pathophysiology, clinical characteristics, and diagnosis of conjunctival papilloma including the use of OCT are discussed. Indications, efficacy, and side effects of currently available management options are also reviewed to guide the selection of the best treatment approach.
摘要：
结膜乳头状瘤是一种获得性良性鳞状细胞肿瘤，可出现在任何年龄，但最常见的是在生命的第三和第四个十年。乳头状瘤与人乳头状瘤病毒（HPV）感染有关，通常类型6和11。尽管组织病理学诊断仍然是金标准，新的非侵入性成像模式的出现，如光学相干断层扫描（OCT）正在改变我们诊断和治疗眼表肿瘤的方式，包括结膜乳头状瘤。这些病变的管理可以证明对治疗医师的挑战,因为并非所有病变都响应于医学和/或手术治疗,并且实际上在手术操作后可能恶化。在这次审查中,流行病学,病理生理学,临床特征,讨论了结膜乳头状瘤的诊断，包括OCT的使用。指示,功效,以及目前可用的管理方案的副作用也进行了审查，以指导选择最佳治疗方法。
