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Abstract：
BACKGROUND: There have been no previous reports on the postnatal course, especially long-term outcomes, of fetal hydrothorax patients, including those treated with thoracoamniotic shunting (TAS) using a double-basket catheter.The outcomes of cases from a single center are reported.
METHODS: Cases of fetal hydrothorax managed at our center between 2005 and 2015 were enrolled retrospectively. TAS was performed if indicated. Long-term outcomes such as cerebral palsy, developmental disabilities, and others were analyzed.
RESULTS: Ninety-two cases of fetal hydrothorax were included. The causes were primary chylothorax, transient abnormal myelopoiesis, cardiac disease, pulmonary sequestration, mediastinal neoplasm, and infection. TAS was performed in 36 cases. Early neonatal death occurred in 19 cases. The 28-day survival rates for all cases and for TAS cases were 70% (48/69) and 72% (26/36), respectively. Of the cases that underwent TAS, one was treated with home oxygen therapy, one was diagnosed with cerebral palsy and severe intellectual disability, and five were diagnosed with mild or moderate developmental disabilities.
CONCLUSIONS: The results showed that the survival rate and long-term outcomes of cases with hydrothorax have improved as TAS has become more prevalent. The reasons for these results need to be elucidated, and efforts are needed to further improve outcomes.
METHODS: Cases of fetal hydrothorax managed at our center between 2005 and 2015 were enrolled retrospectively. TAS was performed if indicated. Long-term outcomes such as cerebral palsy, developmental disabilities, and others were analyzed.
RESULTS: Ninety-two cases of fetal hydrothorax were included. The causes were primary chylothorax, transient abnormal myelopoiesis, cardiac disease, pulmonary sequestration, mediastinal neoplasm, and infection. TAS was performed in 36 cases. Early neonatal death occurred in 19 cases. The 28-day survival rates for all cases and for TAS cases were 70% (48/69) and 72% (26/36), respectively. Of the cases that underwent TAS, one was treated with home oxygen therapy, one was diagnosed with cerebral palsy and severe intellectual disability, and five were diagnosed with mild or moderate developmental disabilities.
CONCLUSIONS: The results showed that the survival rate and long-term outcomes of cases with hydrothorax have improved as TAS has become more prevalent. The reasons for these results need to be elucidated, and efforts are needed to further improve outcomes.
摘要：
背景：以前没有关于产后过程的报道，尤其是长期的结果，胎儿胸水患者，包括使用双篮导管进行胸羊膜分流术（TAS）治疗的患者。报告了来自单个中心的病例的结果。
方法：回顾性纳入2005年至2015年在我们中心治疗的胎儿胸水病例。如果指示,则进行TAS。长期结果，如脑瘫，发育障碍,和其他人进行了分析。
结果：纳入92例胎儿胸水。病因是原发性乳糜胸,短暂性异常骨髓生成,心脏病,肺隔离症,纵隔肿瘤，和感染。36例进行了TAS检查。新生儿早期死亡19例。所有病例和TAS病例的28天生存率分别为70％（48/69）和72％（26/36），分别。在接受TAS的病例中，其中一人接受了家庭氧疗，其中一人被诊断为脑瘫和严重的智力残疾，5人被诊断为轻度或中度发育障碍。
结论：结果显示，随着TAS越来越普遍，胸水患者的生存率和长期结局有所改善。这些结果的原因需要阐明，需要努力进一步改善成果。
方法：回顾性纳入2005年至2015年在我们中心治疗的胎儿胸水病例。如果指示,则进行TAS。长期结果，如脑瘫，发育障碍,和其他人进行了分析。
结果：纳入92例胎儿胸水。病因是原发性乳糜胸,短暂性异常骨髓生成,心脏病,肺隔离症,纵隔肿瘤，和感染。36例进行了TAS检查。新生儿早期死亡19例。所有病例和TAS病例的28天生存率分别为70％（48/69）和72％（26/36），分别。在接受TAS的病例中，其中一人接受了家庭氧疗，其中一人被诊断为脑瘫和严重的智力残疾，5人被诊断为轻度或中度发育障碍。
结论：结果显示，随着TAS越来越普遍，胸水患者的生存率和长期结局有所改善。这些结果的原因需要阐明，需要努力进一步改善成果。
