PDF(Sci-hub)
Abstract：
A-26-year-old man was admitted to our hospital with diffuse abdominal pain, nausea, and vomiting. He had a history of malignant nephrosclerosis, for which he had been receiving peritoneal dialysis (PD) for the past 14 months. His PD effluent was cloudy and turbid (white blood cell count, 10,528/μL; neutrophils 95.2%). A Gram-negative coccobacillus was isolated from peritoneal fluid culture. However, the organism could not be identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) (Vitek MS, bioMérieux), but was identified as Moraxella osloensis by the 16S rRNA gene sequencing. He was successfully treated with intraperitoneal cefazolin therapy for 3 weeks without removing the intra-abdominal catheter. A literature review revealed three previous case reports all of which were diagnosed by MALDI Biotyper (Bruker Daltonics), suggesting that the identification of M. osloensis may vary depending on the type of MALDI-TOF MS system. In conclusion, we experienced a case of M. osloensis infection in a PD patient, which was successfully treated by antibiotic treatment, without removing the PD catheter.
摘要：
一名二十六岁男子因弥漫性腹痛入院,恶心,和呕吐。他有恶性肾硬化病史,在过去的14个月中，他一直在接受腹膜透析（PD）。他的PD流出物混浊（白细胞计数，10,528/μL；中性粒细胞95.2%）。从腹膜液培养物中分离出革兰氏阴性球杆菌。然而,无法通过基质辅助激光解吸/电离飞行时间质谱（MALDI-TOFMS）（VitekMS，bioMérieux)，但通过16SrRNA基因测序鉴定为osloensis莫拉氏菌。他成功地用头孢唑啉腹膜内治疗3周，没有取出腹内导管。文献综述显示，以前的三例病例报告均由MALDIBiotyper（BrukerDaltonics）诊断，表明osloensis的鉴定可能取决于MALDI-TOFMS系统的类型。总之,我们在一名PD患者中经历了一例osloensis感染，通过抗生素治疗成功治疗，没有取出PD导管.
