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Abstract：
Testicular Sertoli cell tumors are extremely rare. Generally, they are benign neoplasms, which belong to a group called sex cord-stromal tumors. In this article, we present a case report of a Sertoli cell tumor, which was accidentally discovered during a urological consultation of a 42-year-old male. An ultrasound showed a 2.1 x 2.2 cm hypoechogenic, hypervascular tumor in the middle third of the left testicle. Serum tumor markers (α-fetoprotein, alkaline phosphatase, β-human chorionic gonadotropin, and lactic dehydrogenase) were all within the normal range. Rapid microscopic evaluation of fresh frozen sections during the operation was inconclusive, which led to a decision not to perform a radical orchiectomy immediately. On formalin-fixed paraffin-embedded (FFPE) sections, the tumor histology showed atypical patterns, and immunohistochemical analysis was performed in order to determine the type of neoplasm and differentiate it from other types of testicular tumors, so as to assign the further course of treatment. Radical inguinal orchiectomy was performed. The final pathology report showed a tumor with no predictive signs of aggressive behavior, which most closely resembled a Sertoli cell tumor.
摘要：
睾丸支持细胞肿瘤极为罕见。一般来说,它们是良性肿瘤，属于性索间质肿瘤。在这篇文章中,我们提供了一个支持细胞肿瘤的病例报告，这是在一名42岁男性的泌尿科咨询中意外发现的。超声显示2.1x2.2厘米的低回声，左睾丸中部三分之一的高血管肿瘤。血清肿瘤标志物(甲胎蛋白，碱性磷酸酶,β-人绒毛膜促性腺激素,和乳酸脱氢酶）均在正常范围内。手术期间新鲜冷冻切片的快速显微镜评估尚无定论，这导致决定不立即进行根治性睾丸切除术。在福尔马林固定石蜡包埋（FFPE）切片上，肿瘤组织学表现出不典型的模式,进行免疫组织化学分析以确定肿瘤的类型并将其与其他类型的睾丸肿瘤区分开来，以便指定进一步的治疗方案。行根治性腹股沟睾丸切除术。最终病理报告显示肿瘤没有攻击性行为的预测迹象，最类似于支持细胞肿瘤。
