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Abstract：
Parry-Romberg syndrome is a rare acquired neurocutaneous disorder typically characterized by hemifacial atrophy. Few cases of bilateral facial involvement have been reported. We report a case of a 60-year-old female with a 20-year history of progressive bilateral facial atrophy. Although an initial diagnosis of acquired partial lipodystrophy was considered, a diagnosis of bilateral Parry-Romberg was favored for three main reasons: (a) lipoatrophy was confined to the face (b) imaging findings of enophthalmos and underlying white matter changes (c) laboratories showing absence of C3 nephritic factor and normal complement levels. The patient was treated with hyaluronic acid fillers with dramatic improvement in cosmetic appearance.
摘要：
Parry-Romberg综合征是一种罕见的获得性神经皮肤疾病，通常以半颜面萎缩为特征。很少报道双侧面部受累的病例。我们报告了一例60岁的女性，有20年的进行性双侧面部萎缩史。尽管考虑了获得性部分脂肪营养不良的初步诊断，对双侧Parry-Romberg的诊断有3个主要原因:(a)脂肪萎缩仅限于面部(b)眼球内孔的影像学表现和潜在的白质改变(c)实验室显示C3肾病因子缺失和补体水平正常.患者用透明质酸填充剂治疗,在美容外观上有显著改善。
