pH 敏感肽功能化纳米粒用于共同递送厄洛替尼和 DAPT 以限制三阴性乳腺癌的进展。
关键词: Triple negative breast cancer erlotinib gamma secretase inhibitor nanoaprticles pH-sensitive tumor targeting
Mesh : Animals Antineoplastic Agents / administration & dosage therapeutic use Cell Line, Tumor Cell Movement / drug effects Cell Survival / drug effects Cell-Penetrating Peptides / chemistry Diamines / administration & dosage therapeutic use Drug Carriers / chemistry Drug Liberation Erlotinib Hydrochloride / administration & dosage therapeutic use Female Humans Hydrogen-Ion Concentration Mice Mice, Inbred BALB C Mice, Nude Nanoparticles / chemistry Oligopeptides / chemistry Receptors, Notch / antagonists & inhibitors Thiazoles / administration & dosage therapeutic use Triple Negative Breast Neoplasms / drug therapy Xenograft Model Antitumor Assays
来 源:
DOI:10.1080/10717544.2019.1576801
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