METHODS: In this retrospective study, we included patients with IBS according to Rome III criteria who had followed a low FODMAP diet. Symptoms scores were measured before and after the low FODMAP diet.
RESULTS: A total of 165 patients (130 females, age 44 ± 14 years) were included. Diarrhea predominant IBS (IBS-D) was present in 40.6% of our patients while JHS was present in 21.2%. The score for abdominal pain was higher for JHS compared to non-JHS prior to intervention (P = 0.011). Symptoms improved in both groups of patients after a low FODMAP diet (P < 0.0001). The largest effects were shown with significant decreases of the average score and bloating. When broken down by JHS and IBS type, a low FODMAP diet significantly improved pain, bloating, diarrhea, constipation, and the average score with the largest effect in JHS/constipation predominant IBS (IBS-C), JHS/mixed IBS and unclassified IBS (IBS-M), JHS/IBS-D, non-JHS/IBS-C and JHS/IBS-M, respectively.
CONCLUSIONS: Our study suggests that a low FODMAP diet has a greater effect on IBS symptoms in JHS than non-JHS patients.
方法:在这项回顾性研究中,我们纳入了符合罗马III标准且遵循低FODMAP饮食的IBS患者.在低FODMAP饮食之前和之后测量症状评分。
结果:总共165名患者(130名女性,年龄44±14岁)。腹泻型IBS(IBS-D)在40.6%的患者中存在,而JHS在21.2%的患者中存在。干预前JHS的腹痛评分高于非JHS(P=0.011)。两组患者在低FODMAP饮食后症状均得到改善(P<0.0001)。最大的效果表现为平均得分和腹胀的显着降低。按JHS和IBS类型细分时,低FODMAP饮食显着改善疼痛,腹胀,腹泻,便秘,和JHS/便秘型IBS(IBS-C)中影响最大的平均得分,JHS/混合IBS和未分类IBS(IBS-M),JHS/IBS-D,非JHS/IBS-C和JHS/IBS-M,分别。
结论:我们的研究表明,与非JHS患者相比,低FODMAP饮食对JHS患者IBS症状的影响更大。