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Abstract：
Rheumatic fever is a rare yet serious condition develop as a consequence of throat infection caused by Streptococcus pyogenes. It is the leading cause for rheumatic heart disease. Rheumatic heart disease is a worldwide public health concern. It is a chronic condition that results in carditis, irreversible valve damage and heart failure in children and young adults living in low-income countries. The age of onset peaks between 5 and 15 years. Approximately, 3% of patients with untreated acute streptococcal sore throats develop rheumatic fever. Rheumatic fever and rheumatic heart disease can be prevented with appropriate antibiotics administration to prevent the progression of valve damage. The current use of primary and secondary prevention antibiotics in Saudi Arabia is not known. Therefore, this clinical practice guideline is developed, based on the best available evidence, to promote appropriate antibiotics secondary prophylaxis use for prevention of rheumatic heart disease.
摘要：
由于化脓性链球菌引起的咽喉感染，风湿热是一种罕见但严重的疾病。它是风湿性心脏病的主要原因。风湿性心脏病是一个全球性的公共卫生问题。这是一种导致心脏炎的慢性病，生活在低收入国家的儿童和年轻人的不可逆转的瓣膜损伤和心力衰竭。发病年龄在5至15岁之间。大约,未经治疗的急性链球菌喉咙痛患者中有3％会出现风湿热。风湿热和风湿性心脏病可以通过适当的抗生素施用来预防，以防止瓣膜损伤的进展。沙特阿拉伯目前使用初级和二级预防抗生素的情况尚不清楚。因此,制定了这个临床实践指南，基于现有的最佳证据,促进适当的抗生素二级预防用于预防风湿性心脏病。
