关键词: IL-15 complex Immunotherapy Mammalian expression PD-1
Mesh : Animals Antineoplastic Agents, Immunological / administration & dosage immunology metabolism Drug Development / methods Female HEK293 Cells HT29 Cells Half-Life Humans Immunoglobulin Fc Fragments / administration & dosage immunology metabolism Immunoglobulin G / administration & dosage immunology metabolism Interleukin-15 / administration & dosage immunology metabolism Interleukin-15 Receptor alpha Subunit / administration & dosage immunology metabolism Mice Mice, Inbred BALB C Programmed Cell Death 1 Receptor / antagonists & inhibitors immunology metabolism Recombinant Proteins / administration & dosage immunology metabolism Xenograft Model Antitumor Assays / methods
来 源:
DOI:10.1016/j.biopha.2019.108677
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