BACKGROUND: Patients with IBS are usually concerned about their diet, which can exacerbate or relieve their symptoms.
METHODS: In this case-control study, ninety cases and 355 controls were selected from a gastroenterology clinic. Dietary intakes of participants were assessed using a validated and reliable food frequency questionnaire (FFQ). Dietary fiber was calculated according to United States Department of Agriculture (USDA) food composition table.
RESULTS: Dietary total fiber intake was significantly associated with lower risk of IBS. The adjusted odds ratio (OR) comparing the highest tertile of dietary total fiber with the lowest tertile was 0.14 (95% CI = 0.71-0.28; P-test for trend <0.001); however, there was no significant association or dose-response trend for higher intakes of soluble, and insoluble fiber separately with risk of IBS.
CONCLUSIONS: Our data indicate that dietary fiber is inversely associated with the risk of IBS. Further prospective studies are needed to confirm these data.
■IBS患者通常关心他们的饮食,这会加剧或缓解他们的症状。
■在本病例对照研究中,从胃肠病诊所选择了90例病例和355例对照。使用经过验证和可靠的食物频率问卷(FFQ)评估参与者的饮食摄入量。根据美国农业部(USDA)食品组成表计算膳食纤维。
■膳食总纤维摄入量与降低IBS风险显著相关。将膳食总纤维的最高三分位数与最低三分位数进行比较的调整比值比(OR)为0.14(95%CI=0.71-0.28;趋势的P检验<0.001);但是,更高的可溶性摄入量没有显著的关联或剂量反应趋势,和不溶性纤维分开与IBS的风险。
■我们的数据表明,膳食纤维与IBS的风险呈负相关。需要进一步的前瞻性研究来证实这些数据。