双特异性抗体的临床试验更新 ,抗体 - 药物缀合物 ,和含抗体的方案治疗急性淋巴细胞白血病。
关键词: Acute lymphoblastic leukemia Antibody-drug conjugate Bispecific antibody Chimeric antigen receptor Hyper-CVAD
Mesh : Adult Antibodies, Bispecific / therapeutic use Antigens, CD19 / immunology Antineoplastic Combined Chemotherapy Protocols / therapeutic use CD3 Complex / immunology Clinical Trials as Topic Female Humans Immunoconjugates / therapeutic use Inotuzumab Ozogamicin / therapeutic use Male Molecular Targeted Therapy / methods Neoplasm, Residual / drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy Protein Kinase Inhibitors / therapeutic use Sialic Acid Binding Ig-like Lectin 2 / immunology
来 源:
DOI:10.1186/s13045-019-0703-z
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