Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (1), role of imaging in drug-related osteonecrosis of the jaw: An up-to-date review (secondary publication).

• 影响指数: 6.468
• 发表时间: Nov 2019
• 来源期刊: Jpn Dent Sci Rev
• DOI: 10.1016/j.jdsr.2018.11.004
• PMID: 30705708
• 文章类型: Journal Article
• 作者列表: Tsuchimochi M,Kurabayashi T

关键词: ARONJ; BRONJ; Bisphosphonate; Imaging diagnosis,; MRONJ

Abstract

MRONJ/ARONJ is a serious adverse effect of medication, although the incidence of the disease is rare, and there are still controversial issues regarding the pathogenesis of MRONJ/ARONJ. Medications that can lead to MRONJ/ARONJ are commonly used to treat osteoporosis and to prevent bone fractures caused by bone metastasis of malignancies. The long-standing disease state of ONJ deteriorates the quality of life of affected patients. Early detection and prevention of the disease are key to alleviating pain and discomfort. To date, several imaging modalities have been introduced to depict the lesions. Imaging modalities, radiography, CT, MRI and nuclear medicine provide important information for managing this challenging disease.