关键词: G protein-coupled receptor kinase 2 adjuvant-induced arthritis fibroblast-like synoviocytes paeoniflorin-6’-O-benzene sulfonate prostaglandin E2
Mesh : Animals Ankle Joint / pathology Antirheumatic Agents / therapeutic use Arthritis, Experimental / drug therapy pathology Arthritis, Rheumatoid / drug therapy pathology Cell Proliferation / drug effects Dinoprostone / metabolism G-Protein-Coupled Receptor Kinase 2 / genetics metabolism Gene Knockdown Techniques Glucosides / therapeutic use Male Monoterpenes / therapeutic use Rats, Sprague-Dawley Receptors, Prostaglandin E, EP4 Subtype / metabolism Synoviocytes / drug effects
来 源:
DOI:10.1038/s41401-018-0196-2
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