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Abstract：
Pellucid marginal degeneration (PMD) is a non-inflammatory ectatic corneal disease characterized by a narrow band of corneal thinning separated from the limbus by a relatively uninvolved area 1-2 mm in width. It is a rare corneal disorder that shares many clinical characteristics with other corneal ectasias, such as keratoconus, keratoglobus or Terrien marginal degeneration. PMD usually starts later in life than keratoconus and progresses slower than keratoconus. Slit-lamp examination is very useful to distinguish PMD from other corneal ectatic disorders with inflammatory nature. Corneal topographic indices and the classical crab-claw topographic pattern cannot be used as the main tool to distinguish between PMD and keratoconus. New Scheimpflug imaging-based devices have shown the importance and usefulness of the pachymetric map for an appropriate diagnosis of PMD. In addition, biomechanical and densitometric properties have been studied as complementary techniques to help in the diagnosis of PMD.
摘要：
透明边缘变性（PMD）是一种非炎性外生性角膜疾病，其特征是狭窄的角膜变薄带，与角膜缘隔开1-2mm宽的相对未受累区域。这是一种罕见的角膜疾病，与其他角膜外翻具有许多临床特征，比如圆锥角膜，角膜缘或Terrien边缘退化。PMD通常比圆锥角膜更晚开始，进展比圆锥角膜慢。裂隙灯检查对于区分PMD与其他具有炎性性质的角膜扩张性疾病非常有用。角膜地形指数和经典的蟹爪地形模式不能作为区分PMD和圆锥角膜的主要工具。新的基于Scheimpflug成像的设备已显示出用于适当诊断PMD的厚度图的重要性和有用性。此外,生物力学和光密度特性已被研究为辅助技术，以帮助诊断PMD。
