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Abstract：
The Zika Virus (ZIKV) has been slowly becoming an epidemic in different parts of the world. Since its discovery in 1947, there have been numerous outbreaks affecting many different populations. Currently, there is an ongoing threat of ZIKV in Latin America and the United States of America. ZIKV is mainly spread by the Aedes aegypti mosquito and causes non-specific symptoms such as fever, myalgia, and generalized weakness. In addition to these symptoms, it has been noted the ZIKV is capable of causing associated conditions in adults, particularly in pregnant women as well as in newborns via vertical transmission. These manifestations include microcephaly, lissencephaly, ventriculomegaly, optic neuropathy, and congenital glaucoma, arthralgia, maculopapular rash, and cardiovascular anomalies such as atrial fibrillation. It is important to understand the reason for this specific set of associated conditions that emerge with ZIKV. This paper aims to identify the manifestations of ZIKV in adults and neonates in detail and attempts to understand the pathophysiology behind each one.
摘要：
寨卡病毒（ZIKV）在世界各地逐渐流行。自1947年发现以来，已经发生了许多影响许多不同人群的疫情。目前,在拉丁美洲和美利坚合众国，ZIKV的威胁持续存在。ZIKV主要由埃及伊蚊传播，并引起发热等非特异性症状，肌痛，和普遍的弱点。除了这些症状,已经注意到ZIKV能够引起成人的相关疾病，特别是在孕妇以及通过垂直传播的新生儿中。这些表现包括小头畸形,间脑,脑室肿大,视神经病变,先天性青光眼,关节痛,斑丘疹,和心血管异常，如心房颤动。重要的是要了解ZIKV出现的特定一组相关条件的原因。本文旨在详细确定ZIKV在成人和新生儿中的表现，并试图了解每种表现背后的病理生理学。
