关键词: clinical outcome colorimetry donor site epidermal graft split-thickness skin graft

Mesh : Aged Aged, 80 and over Cicatrix / physiopathology Epidermis / transplantation Female Humans Male Middle Aged Skin Transplantation / methods Transplant Donor Site / physiology surgery Wound Healing / physiology

来  源:   DOI:10.1111/iwj.13039   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Donor site aesthetic outcomes of epidermal graft (EG) vs split-thickness skin graft (SSG) have yet to be objectively compared. Here, we evaluate donor site healing using a validated scar assessment tool and digital colorimetric technique, which compares colour in a consistent and objective manner. Ten patients (SSG (n = 5) and EG (n = 5)) were included. Donor site scarring was evaluated using the Vancouver Scar Scale (VSS) at Week 6 and Month 3. Colorimetric measurement was performed at Weeks 3 and 6 and Month 3. The mean donor site healing time for EG was significantly shorter (EG: 4.6 days (95% c.i. 3.8-5.3), SSG: 16.8 days (95% c.i. 13.3-20.1) (P = 0.003)). The VSS scores of the EG donor site were lower at Week 6 and Month 3(P < 0.001). The colour match between the donor site and surrounding skin for EG was better compared with SSG at all time points and was almost identical to their surrounding healthy skin at Month 3. This study is the first to objectively measure the clinical appearance of the EG donor site against SSG. EG donor site has faster healing with excellent scarring and good colour match with its surrounding normal skin at all time points compared with SSG.
摘要:
尚未客观比较表皮移植物(EG)与裂层皮肤移植物(SSG)的供体部位美学结果。这里,我们使用经过验证的瘢痕评估工具和数字比色技术评估供体部位的愈合,以一致和客观的方式比较颜色。包括10名患者(SSG(n=5)和EG(n=5))。在第6周和第3个月使用温哥华疤痕量表(VSS)评估供体部位瘢痕形成。在第3周和第6周以及第3个月进行比色测量。EG的平均供体部位愈合时间明显缩短(EG:4.6天(95%c.i.3.8-5.3),SSG:16.8天(95%c.i.13.3-20.1)(P=0.003))。EG供体部位的VSS评分在第6周和第3个月时较低(P<0.001)。在所有时间点,与SSG相比,EG的供体部位和周围皮肤之间的颜色匹配更好,并且在第3个月时与它们周围的健康皮肤几乎相同。这项研究是第一个客观地测量EG供体位点相对于SSG的临床表现。与SSG相比,EG供体部位具有更快的愈合,具有优异的瘢痕形成和在所有时间点与其周围正常皮肤的良好颜色匹配。
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