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Abstract：
During development, the fetal vasculature nourishes the developing lens and retina, and it subsequently regresses after the formation of the retinal vessels. Persistent fetal vasculature (PFV) occurs as a result of a failure of fetal ocular vasculature to undergo normal programmed involution, which leads to blindness or serious loss of vision. Persistent fetal vasculature is responsible for as much as 5% of childhood blindness in western countries. The regulatory mechanisms responsible for fetal vascular regress remain obscure, as do the underlying causes of the failure of regression. Because of recent advancements in microinvasive surgical techniques, the early treatment of PFV has become safer and more effective, thus paving the way for the development of a future new treatment strategy. In this review, clinical and imaging manifestations of PFV and the progress in the treatment of PFV are highlighted.
摘要：
在开发过程中,胎儿脉管系统滋养发育中的晶状体和视网膜，它随后在视网膜血管形成后消退。持续的胎儿脉管系统（PFV）是由于胎儿眼部脉管系统无法进行正常的程序化退化而发生的。导致失明或严重的视力丧失。在西方国家，持续的胎儿脉管系统导致多达5％的儿童失明。负责胎儿血管退化的调节机制仍然不清楚，回归失败的根本原因也是如此。由于微创外科技术的最新进展，PFV的早期治疗变得更加安全和有效，从而为未来新治疗策略的发展铺平了道路。在这次审查中,重点介绍了PFV的临床和影像学表现以及PFV的治疗进展。
