关键词: (43,44,47)Sc radioisotopes Generated impurities level Proton and deuteron beams Radioisotope production Thick Target Yield

Mesh : Calcium Carbonate / radiation effects Cyclotrons Deuterium Humans Poland Protons Radioisotopes / isolation & purification Radiopharmaceuticals / isolation & purification Scandium / isolation & purification Titanium / radiation effects

来  源:   DOI:10.1016/j.apradiso.2018.09.025

Abstract:
Proton and deuteron beams (15.3 and 6.8 MeV, respectively) extracted from the PETtrace medical cyclotron at the Radiopharmaceuticals Production and Research Centre in the University of Warsaw, Heavy Ion Laboratory, 28 MeV protons from the C30 cyclotron at the National Centre for Nuclear Research, Świerk, near Warsaw and 33 MeV protons from the ARRONAX accelerator, Nantes were used to produce and investigate the medically interesting Sc radioisotopes. Both natural and isotopically enriched CaCO3 and TiO2 targets were used (42Ca, 43Ca, 44Ca, 48Ca, 48Ti). The production efficiency and isotopic purity were determined and are reported here for the highest commercially available enrichments of the target material. The Thick Target Yield, Activities at the End of Bombardment (EOB) and the relative activities of produced impurities at EOB are reported for 43Sc, 44gSc, 44mSc and 47Sc produced with particle energies below 33 MeV.
摘要:
质子和氘光束(15.3和6.8MeV,分别)从华沙大学放射性药物生产和研究中心的PETtrace医用回旋加速器中提取,重离子实验室,来自国家核研究中心C30回旋加速器的28MeV质子,wierk,华沙附近和来自ARRONAX加速器的33MeV质子,南特用于生产和研究医学上有趣的Sc放射性同位素。使用了天然和同位素富集的CaCO3和TiO2靶(42Ca,43Ca,44Ca,48Ca,48Ti)。确定了生产效率和同位素纯度,并在此报告了目标材料的最高市售富集率。厚目标产量,轰炸结束时的活性(EOB)和在EOB产生的杂质的相对活性报告为43Sc,44gSc,44mSc和47Sc产生的粒子能量低于33MeV。
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