CD48 和 α 7 烟碱乙酰胆碱受体协同调节 FimH 介导的大肠杆菌 K1 穿透和中性粒细胞在人脑微血管内皮细胞中的迁移。
Mesh : Adhesins, Escherichia coli / genetics metabolism Brain / microbiology CD48 Antigen / metabolism Calcium / metabolism Cell Movement Endothelial Cells / metabolism microbiology Escherichia coli / metabolism pathogenicity Fimbriae Proteins / genetics metabolism Gene Knockdown Techniques Humans Membrane Microdomains Meningitis, Escherichia coli / microbiology pathology Neutrophils / microbiology Signal Transduction Virulence Factors / genetics metabolism alpha7 Nicotinic Acetylcholine Receptor / metabolism
来 源:
DOI:10.1093/infdis/jiy531
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