关键词: Case report Human cell type identification Microbial population profiling

Mesh : Bacteria / genetics Crime DNA Fingerprinting DNA Probes Databases, Nucleic Acid Feces / microbiology Female Humans Likelihood Functions Male Microarray Analysis Microsatellite Repeats Polymerase Chain Reaction

来  源:   DOI:10.1016/j.fsigen.2018.08.018

Abstract:
In forensic case investigations involving human traces, cell type identification has become increasingly important. No longer only the donor of a trace (sub-source level), but also the actions which could have led to the deposition of the trace (\'beyond-the-source\'/activity level) need to be evaluated by forensic experts. For this evaluation determining the cellular source of a DNA profile can be beneficial. In this report two criminal cases are described where both human STR profiling and microbial population profiling were applied to the same trace sample. Human STR profiling was used to evaluate the sub-source question and microbial population profiling was used to evaluate the source question. The Bayesian framework was used to evaluate the evidence.
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