SPZ1 对于耐药乳腺癌细胞的化学抗性和侵袭性至关重要。
关键词: Aggressiveness Breast cancer cells Chemoresistance Chemotherapy SPZ1
Mesh : Animals Antibiotics, Antineoplastic / pharmacology Antineoplastic Agents, Phytogenic / pharmacology Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics metabolism Breast Neoplasms / drug therapy Cell Survival / drug effects Doxorubicin / pharmacology Drug Resistance, Neoplasm Female Gene Expression Regulation, Neoplastic Humans MCF-7 Cells Mice Mice, Nude Middle Aged Neoplasms, Experimental Nuclear Proteins / genetics metabolism Paclitaxel / pharmacology RNA Interference RNA, Small Interfering Twist-Related Protein 1 / genetics metabolism
来 源:
DOI:10.1016/j.bcp.2018.07.046
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