A Case of Non-24-Hour Sleep-Wake Rhythm Disorder Treated With a Low Dose of Ramelteon and Behavioral Education.

• 影响指数: 4.324
• 发表时间: 07 2018 15
• 来源期刊: J Clin Sleep Med
• DOI: 10.5664/jcsm.7244
• PMID: 29991416
• 文章类型: Case Reports
• 中科院分区: Q2
• 方向: 医学
• 作者列表: Watanabe A,Hirose M,Arakawa C,Iwata N,Kitajima T

关键词: behavioral education; circadian rhythm sleep-wake disorders; non-24-hour sleep-wake rhythm disorder; ramelteon

Mesh: Adult; Female; Humans; Indenes / therapeutic use; Patient Education as Topic / methods; Sleep Disorders, Circadian Rhythm / drug therapy physiopathology therapy; Sleep Hygiene / physiology

Abstract

Non-24-hour sleep-wake rhythm disorder (N24SWD) occurs when the intrinsic circadian pacemaker does not entrain (synchronize) to the 24-hour light/dark cycle. There is currently no established treatment for sighted patients with N24SWD. To the best of our knowledge, there have been very few reports on the efficacy of ramelteon administered to sighted patients with N24SWD. We report the case of a sighted patient with N24SWD whose free-running sleep-wake pattern recorded by actigraphy was stopped after the administration of a low dose of ramelteon combined with behavioral education.