果蝇模型在弗里德赖希共济失调研究和治疗中的影响。
关键词: Drosophila melanogaster Friedreich’s ataxia drug screens endoplasmic reticulum frataxin genetic screens iron lipid metabolism metal homeostasis oxidative stress
Mesh : Animals Disease Models, Animal Drosophila melanogaster / genetics physiology Drug Evaluation, Preclinical Friedreich Ataxia / drug therapy genetics pathology Gene Silencing Genetic Predisposition to Disease Humans Iron-Binding Proteins / genetics Lipid Metabolism Oxidative Stress Phenotype Frataxin
来 源:
DOI:10.3390/ijms19071989
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