Abstract：
Wheat is the most commonly grown cereal. Immunological reaction to wheat may be IgE or T-cell- mediated. Asthma could be induced by inhaled flour or by exposure to allergens present in bakery products. In patients with IgE-mediated allergy to wheat proteins there is no specific therapy, except oral immunotherapy (OIT). There are few data regarding OIT with wheat protein in allergic patients. We present a case of a 32-yearold female patient, who worked for 5 years in wheat and bakery products industry, who developed an occupational asthma and chronic urticaria after flour inhalation or ingestion of foods that containit. The patient underwent wheat OIT, that was well-tolerated with no severe reaction during treatment. We may conclude that wheat OIT is a safe therapy and may induce symptoms improvement in allergic asthma and urticaria in patients with wheat allergy. Wheat OIT may induce tolerance to allergic patients.
摘要：
小麦是最常见的谷物。对小麦的免疫反应可以是IgE或T细胞介导的。哮喘可通过吸入面粉或通过暴露于烘焙产品中存在的过敏原而诱发。在IgE介导的对小麦蛋白过敏的患者中，没有特异性疗法，口服免疫疗法（OIT）除外。关于OIT与小麦蛋白在过敏患者中的数据很少。我们介绍了一个32岁的女性患者，在小麦和烘焙产品行业工作了5年，在吸入面粉或摄入含有面粉的食物后患上职业性哮喘和慢性荨麻疹。病人接受了小麦OIT,耐受性良好，治疗期间无严重反应。我们可以得出结论，小麦OIT是一种安全的治疗方法，可以改善小麦过敏患者的过敏性哮喘和荨麻疹的症状。小麦OIT可诱导对过敏患者的耐受性。
