Impact of Clostridium difficile toxin gene PCR result on decisions to de-isolate patients: Do the ends justify the means?

• 发表时间: May 2018
• 来源期刊: J Infect Prev
• DOI: 10.1177/1757177418755309
• PMID: 29796096
• 文章类型: Journal Article
• 作者列表: Morris KA,Davies K,Wilcox MH

关键词: Clostridium difficile; PCR; single room; toxigenic status

Abstract

We aimed to determine how often Clostridium difficile toxin gene PCR assay (CDPCR)-negative patients were appropriately removed from single room contact isolation. Hospital databases were used to collect information on glutamate dehydrogenase (GDH)-positive, toxin-negative inpatients (February-April 2015). Of 60 CDPCR-negative patients, only two (3%) were removed from single room isolation. At least 36% of 53 CDPCR-positive results did not influence bed management. In conclusion, identification of C. difficile toxigenic status did not impact significantly on decisions whether to continue single room isolation. Cost-benefit analysis should be undertaken before CDPCR testing is introduced.