超越检查点抑制 - 与辐射结合的免疫治疗策略。
关键词: Bispecific antibodies CAR, chimeric antigen receptor CAR-T-cells CDN, cyclic dinucleotides CTL, cytotoxic T lymphocyte CTLA-4, cytotoxic T-lymphocyte-associated protein 4 GM-CSF, granulocyte-monocyte colony stimulating factor IR, irradiation Immunocytokines Immunotherapy PD-1, Programmed cell death protein 1 receptor PD-L1, PD-1 ligand Radiotherapy TCR, T cell receptor Treg, regulatory T cells Vaccination bsAb, bispecific antibody scFv, single chain variable fragment
来 源:
DOI:10.1016/j.ctro.2016.12.006
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