关键词: Asthma oral prednisone perimenstrual asthma therapeutic intervention

Mesh : Adult Anti-Asthmatic Agents / administration & dosage therapeutic use Asthma / drug therapy Dose-Response Relationship, Drug Female Humans Menstruation / physiology Phenotype Prednisone / administration & dosage therapeutic use

来  源:   DOI:10.1080/02770903.2017.1418886

Abstract:
Many asthmatic women of childbearing age experience cyclical aggravation of asthmatic symptoms during the perimenstrual period, or perimenstrual asthma (PMA). PMA is considered to be a difficult-to-treat asthma phenotype; conventional asthma therapies are not always effective against PMA.
We report a case of a 27-year-old female with PMA who had received standard asthma treatment since 2013.
The patient showed a dramatic response to therapeutic intervention of oral prednisone, taken for 7 days prior to menstruation each month, in a dose-dependent manner.
Premenstrual treatment with oral prednisone may be a successful new direction for the treatment of PMA, a troublesome type of asthma.
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