Abstract：
Functional magnetic resonance imaging (fMRI) is an advanced tool for the study of brain functions in healthy subjects and in neuropsychiatric patients. This tool makes it possible to identify and locate specific phenomena related to neuronal metabolism and activity. Starting with the detection of changes in the blood supply to a region that participates in a function, more complex approaches have been developed to study the dynamics of neuronal networks. Studies examining the brain at rest or involved in different tasks have provided evidence related to the onset, development, and/or response to treatment in various diseases. The diversity of the possible artifacts associated with image registration as well as the complexity of the analytical experimental designs has generated abundant debate about the technique behind fMRI. This article aims to introduce readers to the fundamentals underlying fMRI, to explain how fMRI studies are interpreted, and to discuss fMRI\'s contributions to the study of the mechanisms underlying diverse diseases of the nervous system.
摘要：
功能磁共振成像（fMRI）是研究健康受试者和神经精神病患者大脑功能的先进工具。该工具可以识别和定位与神经元代谢和活动相关的特定现象。从检测参与功能的区域的血液供应变化开始，已经开发了更复杂的方法来研究神经元网络的动力学。研究检查休息或参与不同任务的大脑提供了与发病有关的证据，发展,和/或对各种疾病的治疗的反应。与图像配准相关的可能伪影的多样性以及分析实验设计的复杂性引起了关于fMRI背后的技术的大量争论。本文旨在向读者介绍fMRI的基本原理，为了解释功能磁共振成像研究是如何解释的，并讨论功能磁共振成像对研究神经系统各种疾病的潜在机制的贡献。
