关键词: Disease Equine Lyme Seroprevalence Treatment Vaccination

Mesh : Animals Anti-Bacterial Agents / therapeutic use Borrelia burgdorferi Consensus Horse Diseases / diagnosis drug therapy epidemiology Horses Lyme Disease / diagnosis drug therapy epidemiology veterinary North America / epidemiology Seroepidemiologic Studies

来  源:   DOI:10.1111/jvim.15042   PDF(Sci-hub)

Abstract:
Borrelia burgdorferi infection is common in horses living in Lyme endemic areas and the geographic range for exposure is increasing. Morbidity after B. burgdorferi infection in horses is unknown. Documented, naturally occurring syndromes attributed to B. burgdorferi infection in horses include neuroborreliosis, uveitis, and cutaneous pseudolymphoma. Although other clinical signs such as lameness and stiffness are reported in horses, these are often not well documented. Diagnosis of Lyme disease is based on exposure to B. burgdorferi, cytology or histopathology of infected fluid or tissue and antigen detection. Treatment of Lyme disease in horses is similar to treatment of humans or small animals but treatment success might not be the same because of species differences in antimicrobial bioavailability and duration of infection before initiation of treatment. There are no approved equine label Lyme vaccines but there is strong evidence that proper vaccination could prevent infection in horses.
摘要:
伯氏疏螺旋体感染在生活在莱姆流行地区的马中很常见,并且暴露的地理范围正在增加。马中B.burgdorferi感染后的发病率未知。记录在案,自然发生的综合征归因于马的B.burgdorferi感染,葡萄膜炎,皮肤假性淋巴瘤.尽管在马匹中报道了其他临床症状,例如跛行和僵硬,这些往往没有很好的记录。莱姆病的诊断是基于暴露于B.burgdorferi,感染液体或组织的细胞学或组织病理学和抗原检测。马中莱姆病的治疗类似于人类或小动物的治疗,但由于抗微生物生物利用度和开始治疗前感染持续时间的物种差异,治疗成功可能不同。目前还没有批准的马标签莱姆疫苗,但有强有力的证据表明,适当的疫苗接种可以预防马的感染。
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