Abstract：
Objective: To evaluate the efficacy and safety of narrow-band intense pulsed light (DPL) in treating facial telangiectasia. Method: Thirty patients with facial telangiectasia underwent five sessions of treatment with DPL (500 nm～600 nm) at 4-week interval. The erythema index (EI), temperature, transepidermal water loss (TEWL), and lightness of the skin (L) were measured before each treatment session and at each follow-up. Result: Thirty cases completed treatment and follow-ups. Twenty-seven cases (90%) got more than 50% clearance post-treatment and among them eight cases (27%) got more than 75% clearance. The average of the mean EI value decreased with the number of treatment sessions; the EI observed after two treatment sessions was significantly different from that observed before treatment (P = 0.012, P < 0.05). The decrease in skin temperature and TEWL values post-treatment was statistically significant (P = 0.000, P = 0.027, P < 0.05), while the L value increased significantly (P = 0.025, P < 0.05). Thirty percent cases had reccurence at 6-month follow-up. While burning sensation, erythema, and swelling were usually seen during the treatment, no severe side effects were observed during treatment and follow-ups. Conclusion: Narrow-band intense pulsed light DPL is effective and safe in treating facial telangiectasia.
摘要：
目的:评价窄带强脉冲光(DPL)治疗面部毛细血管扩张症的疗效和安全性。方法：30例面部毛细血管扩张症患者接受了5次DPL（500nm〜600nm）治疗，间隔4周。红斑指数（EI），温度,经皮水分流失（TEWL），在每次治疗之前和每次随访时测量皮肤的亮度(L)。结果：30例患者完成治疗及随访。治疗后27例（90％）的清除率超过50％，其中8例（27％）的清除率超过75％。平均EI值的平均值随着治疗次数的增加而降低；两次治疗后观察到的EI与治疗前观察到的EI显着不同（P=0.012，P<0.05）。治疗后皮肤温度和TEWL值下降有统计学意义(P=0.000,P=0.027,P<0.05),L值显著升高(P=0.025,P<0.05)。30％的病例在6个月的随访中复发。当灼烧的感觉，红斑,在治疗过程中通常会出现肿胀，在治疗和随访期间未观察到严重的副作用.结论:窄带强脉冲光DPL治疗面部毛细血管扩张症安全有效。
