Gq 活性和 β - 抑制蛋白 - 1 支架介导的 ADGRG2 / CFTR 偶联是男性生育力所必需的。
关键词: ADGRG2 CFTR G protein GPCR arrestin biochemistry chemical biology infertility mouse
Mesh : Animals Cystic Fibrosis Transmembrane Conductance Regulator / genetics metabolism Fertility GTP-Binding Protein alpha Subunits, Gq-G11 / metabolism Male Mice, Inbred C57BL Mice, Knockout Receptors, G-Protein-Coupled / genetics metabolism beta-Arrestin 1 / genetics metabolism
来 源:
DOI:10.7554/eLife.33432
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