Abstract：
Basal cell carcinoma (BCC) is the most common form of human cancer, with a continually increasing annual incidence in the United States. When diagnosed early, the majority of BCCs are readily treated with office-based therapy, which is highly curative. In these evidence-based guidelines of care, we provide recommendations for the management of patients with BCC, as well as an in-depth review of the best available literature in support of these recommendations. We discuss biopsy techniques for a clinically suspicious lesion and offer recommendations for the histopathologic interpretation of BCC. In the absence of a formal staging system, the best available stratification based on risk for recurrence is reviewed. With regard to treatment, we provide recommendations on treatment modalities along a broad therapeutic spectrum, ranging from topical agents and superficially destructive modalities to surgical techniques and systemic therapy. Finally, we review the available literature and provide recommendations on prevention and the most appropriate follow-up for patients in whom BCC has been diagnosed.
摘要：
基底细胞癌（BCC）是人类最常见的癌症形式，在美国，每年的发病率不断增加。早期诊断时，大多数BCC很容易接受基于办公室的治疗，这是非常有效的。在这些基于证据的护理指南中，我们为BCC患者的管理提供建议，以及对支持这些建议的最佳现有文献的深入审查。我们讨论了临床可疑病变的活检技术，并为BCC的组织病理学解释提供了建议。在没有正式暂存系统的情况下，我们对基于复发风险的最佳可用分层进行了综述.关于治疗,我们提供了广泛的治疗方法的建议，从局部药物和表面破坏性方式到手术技术和全身治疗。最后,我们回顾了现有文献,并就已诊断为BCC的患者的预防和最合适的随访提供建议.
