关键词: 16p11.2 CNV autism deletion duplication iPSC macrocephaly microcephaly neurodevelopmental disorders neurons
Mesh : Autism Spectrum Disorder / genetics metabolism Autistic Disorder / genetics metabolism Cell Differentiation / genetics physiology Chromosome Deletion Chromosome Duplication / genetics Chromosomes, Human, Pair 16 / genetics DNA Copy Number Variations / genetics Humans Induced Pluripotent Stem Cells / cytology metabolism Megalencephaly / genetics metabolism Microcephaly / genetics metabolism Models, Genetic Neurons / cytology metabolism
来 源:
DOI:10.1016/j.celrep.2017.11.037
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