关键词: Diabetes Hemoglobin A1c Joint surgery Postoperative Surgical risk

Mesh : Arthroplasty, Replacement / adverse effects Diabetes Complications / blood surgery Diabetes Mellitus / blood therapy Elective Surgical Procedures / adverse effects Evidence-Based Medicine Glycated Hemoglobin A / analysis Humans Hyperglycemia / prevention & control Postoperative Complications / epidemiology etiology prevention & control Risk Wound Healing

来  源:   DOI:10.1016/j.jdiacomp.2017.08.016   PDF(Sci-hub)

Abstract:
Patients with diabetes mellitus are known to have a high risk of postoperative complications, including infections, impaired wound healing, cardiovascular events, venous thromboembolism, and mortality. Because hyperglycemia has been thought to mediate this risk, there is a clinical propensity for improving glycemic control, as assessed by hemoglobin A1c (HbA1c) level, prior to proceeding with elective surgery, particularly joint replacement surgery. However, it is not established whether chronic poor glycemic control, indicated by elevated HbA1c levels, predicts increased risk of postoperative complications. The benefit of improving glycemic control must be weighed against risks of delaying necessary elective surgery, such as joint replacement surgery, which risks may include negative impact on long-term glycemic control. Thus, we review the current evidence to determine the relationship between HbA1c and postoperative surgical risk, especially on joint replacement surgery.
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