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Abstract：
Patients diagnosed with skin conditions have a higher risk of comorbid psychiatric conditions and suicide-related outcomes such as suicidal ideations and behaviors. There is paucity of evidence in the US general population about the risk of suicide death in patients with dermatologic conditions.
We conducted a retrospective case-control study to investigate the risk of suicide death in patients receiving care for dermatologic conditions. This study involved 8 US health systems. A total of 2674 individuals who died by suicide (cases) were matched with 267,400 general population control individuals.
After adjusting for age, sex, and any mental health or substance use condition, we did not find an association between death by suicide and any skin condition including conditions where clinicians are generally concerned about the risk such as acne (adjusted odds ratio [aOR] = 1.04, p = 0.814), atopic dermatitis (aOR = 0.77, p = 0.28), and psoriasis (aOR = 0.91, p = 0.64).
This case-control study provides no evidence of increased risk of death by suicide in individuals with major skin disorders in the US general population.
We conducted a retrospective case-control study to investigate the risk of suicide death in patients receiving care for dermatologic conditions. This study involved 8 US health systems. A total of 2674 individuals who died by suicide (cases) were matched with 267,400 general population control individuals.
After adjusting for age, sex, and any mental health or substance use condition, we did not find an association between death by suicide and any skin condition including conditions where clinicians are generally concerned about the risk such as acne (adjusted odds ratio [aOR] = 1.04, p = 0.814), atopic dermatitis (aOR = 0.77, p = 0.28), and psoriasis (aOR = 0.91, p = 0.64).
This case-control study provides no evidence of increased risk of death by suicide in individuals with major skin disorders in the US general population.
摘要：
诊断为皮肤疾病的患者患精神疾病和自杀相关结果如自杀意念和行为的风险更高。在美国普通人群中，缺乏关于皮肤病患者自杀死亡风险的证据。
我们进行了一项回顾性病例对照研究，以调查接受皮肤病治疗的患者自杀死亡的风险。这项研究涉及8个美国卫生系统。共有2674名因自杀而死亡的人（病例）与267,400名普通人群对照者相匹配。
调整年龄后，性别,以及任何精神健康或物质使用状况，我们没有发现自杀死亡与任何皮肤状况之间的关联，包括临床医生普遍关注痤疮等风险的状况（调整后的比值比[aOR]=1.04，p=0.814），特应性皮炎（aOR=0.77，p=0.28），和银屑病（aOR=0.91，p=0.64）。
这项病例对照研究没有提供证据表明美国普通人群中患有严重皮肤病的个体自杀死亡风险增加。
我们进行了一项回顾性病例对照研究，以调查接受皮肤病治疗的患者自杀死亡的风险。这项研究涉及8个美国卫生系统。共有2674名因自杀而死亡的人（病例）与267,400名普通人群对照者相匹配。
调整年龄后，性别,以及任何精神健康或物质使用状况，我们没有发现自杀死亡与任何皮肤状况之间的关联，包括临床医生普遍关注痤疮等风险的状况（调整后的比值比[aOR]=1.04，p=0.814），特应性皮炎（aOR=0.77，p=0.28），和银屑病（aOR=0.91，p=0.64）。
这项病例对照研究没有提供证据表明美国普通人群中患有严重皮肤病的个体自杀死亡风险增加。
