关键词: Aggressive fibromatosis Augmentation mammaplasty Breast augmentation Breast desmoid Desmoid tumor Silicone implant

Mesh : Age Distribution Aged Biopsy, Needle Breast Implants / adverse effects Breast Neoplasms / chemically induced epidemiology pathology Female Fibromatosis, Aggressive / chemically induced epidemiology pathology Humans Immunohistochemistry Incidence Israel Mammaplasty / adverse effects methods Middle Aged Prognosis Rare Diseases Risk Assessment Silicone Gels / adverse effects chemistry

来  源:   DOI:10.1007/s00266-017-0948-2   PDF(Sci-hub)

Abstract:
BACKGROUND: Desmoid tumors are borderline tumors of the connective tissue, arising in the musculo-aponeurotic stromal elements. A desmoid tumor (DT) has an infiltrative and locally aggressive growth pattern and usually does not metastasize; however, it has a high recurrence and complication rate. DT located in the breast (BDT) represents a rare extra-abdominal form. Recently, the presence of breast silicone implants was suggested by several researchers as a risk factor for developing BDT.
OBJECTIVE: The goal of this review is to investigate the possible correlation between BDT and breast implant surgery.
METHODS: We conducted a literature review of BDT-reported cases, associated with breast implant surgery.
RESULTS: The search revealed 36 cases of BDT associated with silicone breast implants.
CONCLUSIONS: Based on the reviewed data, the incidence of BDT following breast implant surgery is lower than BDT in the general population. At the moment, a possible association between breast implants and the development of breast desmoid tumors cannot be unequivocally confirmed. A world registry with accurate documentation of each case of BDT associated with breast implant surgery should be performed for future investigation.
UNASSIGNED: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to Table of Contents or the online Instructions to Authors www.springer.com/00266 .
摘要:
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