关键词: cancer lymphoma in foot mantle cell lymphoma skin involvement tumor

Mesh : Aged, 80 and over Diabetic Foot / diagnosis pathology Diagnosis, Differential Disease Progression Foot / pathology Humans Lymphoma, Mantle-Cell / diagnosis pathology surgery Male Neoplasm Invasiveness / pathology Neoplasm Staging Rare Diseases Risk Assessment Skin Neoplasms / diagnosis pathology surgery Treatment Outcome

来  源:   DOI:10.1053/j.jfas.2017.04.019   PDF(Sci-hub)

Abstract:
Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that commonly affects extranodal sites. The most commonly affected sites are the bone marrow, gastrointestinal tract, Waldeyer\'s ring, lung, and pleura. We report the case of an 80-year-old diabetic male, in MCL remission, who presented with a small dome-shaped nodule on his calf and an ipsilateral second digit non-healing ulceration after a traumatic fall. Despite surgical and conservative treatment, the wound worsened, resulting in histopathologic examination, which confirmed the presence of lymphocytes, indicating MCL relapse. This case was followed up for approximately 3 months until the patient died. Our case is an example of pedal manifestations of skin involvement of MCL, which, on consideration of the clinical manifestations also, can be confused with a nonhealing diabetic wound. The clinical significance of our case study is to assist in the diagnosis, management, and prognosis of a patient with MCL.
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