妊娠中系统性皮质类固醇的使用以及选择妊娠和出生结局的风险。A Review of Systemic Corticosteroid Use in Pregnancy and the Risk of Select Pregnancy and Birth Outcomes.-医云文献数字医云科研云海量医学决策数据服务

Abstract：

The evidence to date regarding corticosteroid exposure in pregnancy and select pregnancy and birth outcomes is limited and inconsistent. The authors provide a narrative review of published literature summarizing the findings for oral clefts, preterm birth, birth weight, preeclampsia, and gestational diabetes mellitus. Whenever possible, the results are limited to oral or systemic administration with a further focus on use in autoimmune disease. Although previous studies of corticosteroid exposure in pregnancy reported an increased risk of oral clefts in the offspring, more recent studies have not replicated these findings.

摘要：

迄今为止，关于妊娠中皮质类固醇暴露以及选择妊娠和分娩结局的证据有限且不一致。作者提供了已发表文献的叙述性综述，总结了口腔裂痕的发现，早产,出生体重,先兆子痫,和妊娠期糖尿病。只要有可能,结果仅限于口服或全身给药，进一步关注自身免疫性疾病的应用。尽管以前的研究报告说，怀孕期间皮质类固醇暴露的后代口腔裂痕的风险增加，最近的研究没有复制这些发现。