关键词: 45S5 BG scaffolds Coating HA nanoparticles Mechanical properties

Mesh : Ceramics / analysis Durapatite / analysis Glass / analysis Materials Testing Nanocomposites / analysis Polyesters Tissue Engineering Tissue Scaffolds

来  源:   DOI:10.1016/j.jmbbm.2017.07.012

Abstract:
The purpose of this study is to analyze the mechanical enhancement provided by nanocomposite coatings deposited on robocast 45S5 bioglass (BG) scaffolds for bone tissue regeneration. In particular, a nanocomposite layer consisting of hydroxyapatite (HA) nanoparticles, as reinforcing phase, in a polycaprolactone (PCL) matrix was deposited onto the surface of the BG struts conforming the scaffold. Three different HA nanopowders were used in this study. The effect of particle size and morphology of these HA nanopowders on the mechanical performance of 45S5 BG scaffolds is evaluated.
摘要:
这项研究的目的是分析沉积在robocast45S5生物玻璃(BG)支架上用于骨组织再生的纳米复合涂层提供的机械增强作用。特别是,由羟基磷灰石(HA)纳米颗粒组成的纳米复合层,作为强化阶段,在聚己内酯(PCL)中,将基质沉积到符合支架的BG支柱的表面上。在本研究中使用了三种不同的HA纳米粉末。评估了这些HA纳米粉体的粒径和形态对45S5BG支架力学性能的影响。
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